Newly identified mechanism could be target for new therapies.

Studying triggers in cells’ transition from colitis to cancer, UF colorectal surgeon Emina Huang, M.D., has found blocking two hormones could inhibit tumor growth.

University of Florida scientists explain why two subtypes of HIV-1 — the virus that causes acquired immunodeficiency syndrome, or AIDS — held steady at relatively low levels for more than 50 years in west central Africa before erupting as an epidemic in east Africa in the 1970s.

Research at UF suggests how new, therapeutic genes that have been irrevocably delivered to the human brain to treat Parkinson’s can be controlled if the genes unexpectedly start causing problems.

Three patients, apparently for the first time in their lives, were able to produce trace amounts of the protective form of a protein called alpha-1 antitrypsin for up to one year, a potential step toward a gene therapy for about 100,000 Americans with alpha-1 antitrypsin deficiency.

College of Medicine researchers were able to program bone marrow stem cells to repair damaged retinas in mice, a discovery that has implications for a range of diseases.

Researchers with the McKnight Brain Institute of the University of Florida discovered that inflammation of microglia — an abundant cell type that plays an important supporting role in the brain — does not appear to be associated with dementia in Alzheimer’s disease. The finding could influence how scientists proceed with Alzheimer’s therapies.

Researchers identify new cellular target for HIV drug development.

A UF colorectal surgeon identifies a biomarker for colon cancer stem cells, which she believes will help researchers better target the possible ‘root’ of the disease.

A growth factor used to rescue dying brain cells may cause unwanted weight loss.